What Causes ALS?

ALS is a varied and mysterious disease. In more than 90% of cases diagnosed, no clear identifying cause of the disease is apparent. Also, nothing about patients’ lifestyles gives scientists and clinicians clues as to what causes ALS. Diet, geography, lifestyle choices or history all fail to explain why patients have developed this late onset, fully developed and progressive disease.

In approximately 5 percent of cases, a clear genetic history does exists. The disease is classed as autosomal dominant in these patients, which is to say that almost half of all family members show a clear history of ALS.